Usually, when there is a symptom of erectile dysfunction, the doctor recommends taking the drug Viagra 25 mg or 50 mg. This is the standard starting dose for men of any age. Increase it is only in the absence of the expected effect. The optimal option is the tablets with an active substance content of 50 mg. If necessary, they are easily divided in half. As a result, one package turns into two with a smaller dosage. In this way, you can save a lot of money on buying medicines.
To stimulate the sexual system, you need sexual stimulation. Without it, even after taking the pill an erection does not occur!
How does Viagra work 50 mg
Tablets Viagra for men 50 mg help to get rid of erectile dysfunction. They completely restore the broken mechanism of an erection. The pharmacodynamic properties are based on the ability of the active substance to block the enzyme PDE-5. It is he that destroys cGMP in the cavernous bodies of the penis, thus preventing the process of excitation. The result of blocking phosphodiesterase is a significant increase in NO and cGMP in the blood.
The principle of action of the drug Viagra 50 mg is to accelerate the circulation. This happens 15-20 minutes after taking the medicine. Increased blood flow observed in the genital area. Nitric oxide relaxes smooth muscles and allows blood to pour into the penis. On the perimeter of the trunk of the penis there are cavernous bodies that begin to actively absorb blood. This leads to their swelling, hardening, increasing in size.
Pharmacokinetic properties
Cenforce 50 mg is absorbed by the body immediately after ingestion. If the tablet is taken on an empty stomach, the peak of the active substance content in the blood is observed after 25-30 minutes (on average 60 minutes). Bioavailability of the drug is 23-65% (an average of 42%). In the equilibrium state, the volume of distribution of the active substance is 106 liters. In other words, the drug disperses evenly throughout the body. After a few hours, it begins to be metabolized by liver isoenzymes (mainly CYP3A4, partially CYP2C9). The resulting desmethyl metabolite is released outside (half-life on average 4 hours).
Indications for use
Viagra sildenafil 50 mg tablets are intended only for the treatment of erectile dysfunction. They in no way affect the duration of sex and the delay in ejaculate ejection. The drug is approved for admission to men aged 18-65. In older age, it is recommended to use a medicine in a dose of 25 mg. For women, this tool is not intended. In the pharmacy “ShopStoyal” you can buy Viagra 50 mg without a prescription. This is done solely for the convenience of customers and improving the quality of service. Nevertheless, we strongly recommend that you consult with your doctor before buying.
Dosing and Administration
Cenforce 50 mg is one of the best treatments for impotence. Customer testimonials show that when properly taken, the desired effect is achieved on average 45-60 minutes. Therefore, you need to drink a pill an hour before sex. It is advisable to do this not earlier than 2-3 hours after eating. The denser the food, the more time must pass. Otherwise, the effect may appear with a delay. In addition, fatty foods can reduce the effectiveness of the active ingredient. It is strictly forbidden to drink alcoholic beverages, grapefruit or grapefruit juice during the reception.
If you have not yet chosen between doses of Viagra 50 or 100 mg, stop at the first. According to medical statistics, this dosage is optimal for most men. Those who had not previously taken Viagra, doctors recommend 25 mg. But in this case, too, it is worth taking a closer look at Senforos. In tablets with different contents of the active substance, the price in pharmacies is approximately the same. Therefore, you can divide Cenforce-50 in half and get two tablets at the price of one.